This collection includes slides and videos from Day 2 of the 2021 SEI Research Review event. These sessions include presentations, lightning talks, and collaboration conversations. Day 2 sessions include Collaboration Conversation on Scalable Assurance of Safety-Critical Systems, Multicore Confidence, Rapid Certifiable Trust, Towards Incremental and Compositionally Verifiable Security for CHIC-Centric Cyber Physical Systems, Combined Analysis for Source Code and Binary Code for Software Assurance, Rapid Adjudication of Static Analysis Alerts During Continuous Integration, and Collaboration Conversation on Digital Engineering.